Objective: In this article, a motor skill disorder called Developmental coordination disorder (DCD), that is usually first diagnosed during childhood, is explained and discussed. In the year 1987, DCD was formally recognized as a distinct disorder in children by the American Psychiatric Association (APA). DCD is a generalized term for the children who have some degrees of impairment in the development of motor coordination and therefore have difficulties with physical skills which significantly interfere with their academic achievements and /or performing everyday activities. As they develop, other age-related tasks are also below average. Because these impairment & conditions are often associated with emotional distress, they can seriously interfere with the person’s everyday life and social relationships. Reviews indicate that most of the training procedures have only a limited effect on the development of general coordination, and that they have no effect at all on academic progress. This includes approaches based on assumed underlying deficiencies such as sensory integration deficits and kinesthetic functioning deficits, as well as the more traditional perceptual - motor training. One new approach is Cognitive Orientation to daily Occupational Performance (CO-OP), based on problem – solving strategies and guided discovery of the child and task specific strategies. The aim of this article was to inform, promote and disseminate more information about some difficulties in applying the diagnostic criteria for DCD. Also, a brief review of the researches on the intervention methods is presented.

Background: disorder of sex development (DSD) is defined as a congenital mismatch between sex phenotype, gonadal and sex chromosome, which mainly present with atypical genital appearance or ambiguous genitalia. It consider as a medical emergency and the cases should be evaluate immediately for detection of life threatening conditions and determination of gender.Case Report: We report a 50 days old infant with 49,XXXXY syndrome presenting with ambiguous genitalia. Conclusion: 49,XXXXY syndrome is a rare sex chromosome aneuploidy disorder, which represented with its “classical triad” consists of mental retardation, radioulnar synostosis and hypogonadism.  

Introduction: Through the present research, it was hoped to provide solid evidence concerning the definitions, assessments and some treatments of Developmental coordination disorder (named hereafter as DCD).Materials and Methods: To locate related articles on the topic of DCD, Google scholar, Proquest, PubMed, Science Direct and Cochrane library databases were reviewed. The arrangement of the article is as follows: After introducing the disorder and discussing reasons for early identification, some treatment methods are expressed.Results: At the present state of art, no diagnostic tool has been offered for DCD. The disorder does not seem to ameliorate with time, and in long term, negative secondary consequences may occur.Conclusion: More researches for early diagnosis and appropriate treatments of this disorder are required and the professionals need to be equipped with appropriate information resources on the subject.

Objective: According to the Diagnostic and Statistical Manual of Psychiatric disorders-Fifth Edition, Autism Spectrum disorders (ASDs) are neuroDevelopmental disorders associated with persistent defects in social communication and interactions, patterns, interests, behaviors, and repetitive and limited activities. In other words, ASDs are a lifelong condition characterized by widespread problems in social interaction and communication, stereotypical behaviors and limited interests. The early diagnosis of ASD can lead to early intervention and improvement of Developmental outcomes. Parental screening tools are the ideal tools for the timely detection of ASD because they provide diagnostic information from the person familiar with the child and are easy to perform and score. This study aimed to standardize the Pervasive Developmental disorder Screening Test (PDDST), which screens these disorders at an early age (12 to 48 months). This test consists of 36 questions that are answered as “Yes-No.”Materials & Methods: The population of this descriptive study included all children aged below 8 years with neuroDevelopmental disorders and normal children of the same age group in Tehran. In relation to autistic children, the criteria for diagnosis were the persistent impairment of social communication and social interactions in different situations, and patterns of behavior and limited repetitive activities as assessed by a specialist and a psychiatrist. In relation to normal children, the inclusion criteria were the lack of these problems.Thus, a total of 252 children, i.e., 205 children with neuroDevelopmental disorders (autism 135 and intellectual disability 70) and 47 normal children (to determine discriminant validity), were included as the sample for this study. Among them, 97 were girls and 157 were boys. The parents of the participants responded to screening tests within 10 minutes at the psychiatric clinics and hospitals in Tehran. The test validity through content by experts and the differential method with variance analysis technique, which shows the significance of the difference between the three groups of participants in the score obtained from the test, and the validity was calculated through the coefficient of internal consistency of Kuder–Richardson 20. Two criteria of validity (sensitivity and specificity) were used to determine the cutting point. Data analysis was performed using the SPSS V.21 software.Results: The content validity of the test was confirmed according to the experts’ judgments. The results of discriminant validity revealed that there is a significant difference between groups (P=0.001). It was also found that the means of normal, intellectual disability, and autistic groups are, respectively, from the lowest to the highest. The reliability of the test was 0.73. The sensitivity of the child’s screening for ASD is indicative of the accuracy of the screening of a child without ASD. The results of this study showed that the PDDST-II screening test for both sensitivity and specificity indices were in a favorable situation and could correctly identify children with autism and children without autistic dysfunction. The two sensitivity and specificity indicators in the score of 5 reached their highest, so the cut-off point for the test was scored at 5 and more.Conclusion: The results of this study showed that the psychometric properties of the PDDST-II screening test are suitable for discriminating between children with ASD and those with other Developmental disorders such as mental retardation and normal children. This test also had a good reliability coefficient and is suitable for diagnosing children with ASD.